Living rules to prevent COVID-19

PREVENTION METHOD THE REASON
Temperature

The optimal temperature for coronaviral proliferation is 33 °C. This temperature is the normal temperature in the upper respiratory tract. Hence, to keep the temperature in the upper airway more than 33°C is recommended.

Humidity In cold and dry state, the viability of coronavirus is high.
Facial mask Facial mask filters viral droplets and makes human upper airway keep warm and humid.
Air conditioner, Room temperature.

Room temperature is 20 ~ 22 °C. In this temperature zone, the temperature of the upper airway is 33 °C. To keep the upper airway in more than 33°C, the room temperature should be more than 23°C

As my personal experience considering both temperature and humidity, the adequate temperature of air-conditioner may range from 25 to 27°C. 

Soap, Disinfectant   
Ethanol, Disinfectant Ethanol plays a role in breaking enevelope of coronavirus.
Bitter herbs, Food Bitter herbs help our immunity boost.
Mediterranean diet Meditteranean diet helps our immunity boost.

For detailed explanation, refer to category "2019-nCoV, COVID-19" within this blog.

 

 

 

 

AUTHOR: SEOK WOO YANG, MD & PhD (E mail: soplab@outlook.kr)

DATE:2020.03.09

CONTENT:

 

ORGAN ANATOMIC PATHOLOGIC FINDINGS CLINICAL IMPLICATION
Lung

Diffuse alveolar damage.

Desquamation of pneumocytes.

Hyaline membrane disease.

Intra-alveolar fibromyxoid exudate.

Pulmonary edema.

Interstitial mononuclear cell infiltration, predominantly lymphocytes.

Multinucleated syncytial cells with atypical enlarged pneumocytes characterised by large nuclei, amphophilic granular cytoplasm, and prominent nucleoli.[1]

 

Acute respiratory distress syndrome.

Acute lung injury.

Heart Interstitial mononuclear inflammatory infiltrates  
Liver

Moderate microvesicular steatosis.

Mild lobular and portal activity.[1]

 
Kidney in COVID-19

No datum.

 
Kidney in MERS-CoV

Acute kidney injury.

Tubular epithelial cell degnerative/regenerative change.[2]

Kidney failure.
Central nervous system in COVID-19 No datum.  
Central nervous system in SARS-CoV Viral particles rich in brain neurons.[3] A potential neuroinvasion

 

REFERENCE:

[1] Xu Z, Shi L, Wang Y, Zhang J, Huang L, Zhang C, Liu S, Zhao P, Liu H, Zhu L, Tai Y, Bai C, Gao T, Song J, Xia P, Dong J, Zhao J, Wang FS. Pathological findings of COVID-19 associated with acute respiratory distress syndrome. Lancet Respir Med. 2020 Feb 18:S2213-2600(20)30076-X

[2] Alsaad KO, Hajeer AH, Al Balwi M, Al Moaiqel M, Al Oudah N, Al Ajlan A, AlJohani S, Alsolamy S, Gmati GE, Balkhy H, Al-Jahdali HH, Baharoon SA, Arabi YM. Histopathology of Middle East respiratory syndrome coronovirus (MERS-CoV)
infection - clinicopathological and ultrastructural study. Histopathology. 2018 Feb;72(3):516-524.

[3] Li YC, Bai WZ, Hashikawa T. The neuroinvasive potential of SARS-CoV2 may be at least partially responsible for the respiratory failure of COVID-19 patients. J Med Virol. 2020 Feb 27.

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